DUPIXENT® – Dosing and administration
Administered by subcutaneous injection
DUPIXENT® is intended for use under the guidance of a healthcare provider. A patient may self-inject DUPIXENT® or the patient’s caregiver may administer DUPIXENT®.
In adolescents 12 years of age and older, it is recommended that DUPIXENT® be administered by or under the supervision of an adult. The DUPIXENT® pre-filled pen is only for use in adults and adolescents aged 12 years and older. The DUPIXENT® pre-filled syringe should be given by a caregiver in children 6-11 years of age.
Provide proper training to patients and/or caregivers on the preparation and administration of DUPIXENT® prior to use, according to the Instructions for Use.1
DUPIXENT® can be used with or without topical corticosteroids. Topical calcineurin inhibitors may be used, but should be reserved for problem areas only, such as the face, neck, intertriginous and genital areas.1
Please see the Product Monograph for complete dosing and administration instructions.
DUPIXENT® is not a steroid treatment or an immunosuppressant. DUPIXENT® is an immunomodulator.1
Preparation for use1
• Before injection, instruct patients and/or caregivers to remove the DUPIXENT® pre-filled syringe or pre-filled pen from the refrigerator.
• 300 mg pre-filled syringe or pen: allow DUPIXENT® to reach room temperature by waiting 45 minutes.
• 200 mg pre-filled syringe or pen: allow DUPIXENT® to reach room temperature by waiting 30 minutes.
• Patients and/or caregivers should inspect DUPIXENT® for particulate matter and discoloration prior to administration.
• Patients and/or caregivers should not use the pre-filled syringe/pen if the liquid contains visible particulate matter, or is discolored or cloudy (other than clear to slightly opalescent, colorless to pale yellow).
• Patients and/or caregivers should discard any unused product remaining in the pre-filled syringe/pen in accordance with local requirements.
Important administration instructions1
• Patients and/or caregivers should read the Instructions for Use prior to injecting.
• Instruct patients and/or caregivers to administer subcutaneous injection into the thigh or abdomen, except for the 2 inches (5 cm) around the navel.
• The upper arm can also be used if a caregiver administers the injection.
• It is important to rotate the injection site with each injection. DO NOT inject DUPIXENT® into skin that is tender, damaged, bruised, or scarred. DO NOT inject through clothes.
• Choose a different injection site for each DUPIXENT® injection. If you need a second injection to complete your dose then leave at least 5 cm (2 inches) between the two injection sites.
Invite your patients to watch our injection training videos so they can see how to inject DUPIXENT®.
Self-injection
For caregivers
Storage and Handling1
DUPIXENT® should be refrigerated at 2–8°C, never frozen or exposed to extreme heat
DUPIXENT® is light-sensitive, so it should be kept in its carton in order to protect it from light
Do not shake DUPIXENT® or use beyond the expiry date
DUPIXENT® may be kept at room temperature (up to 25°C) for up to 14 days
After removal from the refrigerator, DUPIXENT® must be used within 14 days or discarded
Freedom Support Program
Find out what the Freedom Support Program can bring to your patients and how you can help them access it.
Connect With a Rep
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DUPIXENT®, Sanofi and Freedom logos are trademarks of Sanofi, used under license by sanofi-aventis Canada Inc.
REGENERON® is a trademark of Regeneron Pharmaceuticals, Inc. All rights reserved.
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MAT-CA-2300298
Last updated: 06/2023
