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Hi there. Thanks for watching.
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Today we’re going to show you how to properly inject a dose of DUPIXENT® (dupilumab) using the single-dose pre-filled pen.
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I know you’ve already learned how to give an injection with your healthcare provider.
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We are here to guide you through your first at-home experience.
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First thing we’ll go over is what supplies to gather, how to prep the injection area,
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how to inject the dose and discard your single-dose pre-filled pen.
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If you haven’t yet read the instructions for use, located in your DUPIXENT® treatment package, pause the video and take a look.
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It has step-by-step instructions, which I will go through with you today.
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It’s important to read all of the instructions carefully before using the pre-filled pen.
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Let’s take a closer look at the pre-filled pen.
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I found it helpful to review the different parts of the pre-filled pen
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like the cap, the window, and the needle cover before handling the pre-filled pen itself.
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OK, it’s time for your DUPIXENT® injection. Are you ready?
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Yeah.
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Feel free to watch us and follow along as I give an injection.
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Depending on your dose, your box of DUPIXENT® may be a different colour. This is the box for the 300 mg dose.
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Before we start, here are some guidelines.
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Keep the pre-filled pen and all medicines out of the reach of children.
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Keep unused pre-filled pens in the original carton
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and store in the refrigerator between 2ºC to 8ºC, or 36º to 46ºF.
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To begin, take your medication out of the refrigerator.
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Take one pen out of the packaging by holding the middle of the pen body.
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Now, let’s check the label on the pen to ensure that the medication and dosage strength are correct,
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and the expiration date has not passed.
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Do not use the pen if the expiration date has passed.
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If the dosage strength or expiration date isn’t right, contact your pharmacy.
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Next take a look at the medicine through the viewing window.
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The liquid inside should be clear and colorless to pale yellow.
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You may see an air bubble. This is totally normal.
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Do not inject DUPIXENT® if the liquid inside is discoloured, cloudy, or contains visible flakes or particles.
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Do not use the pre-filled pen if the window is solid yellow.
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Do not use the pre-filled pen if it’s been damaged.
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Do not use the pre-filled pen if the cap is missing or not securely attached.
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If you have any questions about whether the pen is ok to use, please call the Freedom support program, or your healthcare provider.
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If you have an unused pre-filled pen, return it to the refrigerator in the original carton to protect it from the light.
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Lay the pre-filled pen on a flat surface and let it naturally warm to room temperature.
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Do not freeze or heat the pre-filled pen.
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Do not put the pre-filled pen into direct sunlight.
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Throw away any pre-filled pen that’s been left at room temperature for more than 14 days.
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On that note, if you ever need to remove a DUPIXENT® carton from the refrigerator,
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it’s a good idea to write down the date of removal in the space provided on the outer carton,
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so that you can remember to use DUPIXENT® within 14 days.
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Do not shake the pre-filled pen at any time.
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As the pen warms up, let’s gather some additional materials you’ll need for the injection.
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You’ll need a cotton ball or gauze, an alcohol wipe, and a puncture resistant disposal container.
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If you don’t have a puncture resistant disposal container, call your pharmacy,
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the Freedom support program,
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or your healthcare provider to request a puncture-resistant disposal container.
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Now take your supplies to an area where you and your child can sit comfortably.
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I prefer the comfort of our living room couch. You might prefer the bathroom or your bedroom for privacy.
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We’re almost ready to inject DUPIXENT®.
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First, let’s wash our hands thoroughly with soap and water.
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Next, let’s choose an injection site.
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Both the stomach and thigh are acceptable except for the 5 centimeters or 2 inches around the belly button.
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The outer area of the upper arm is also an option since you are giving the injection to someone,
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but not if you are self-injecting.
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Be sure to choose a different site each time you inject DUPIXENT®.
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Do not inject through clothes.
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Do not inject into skin that is tender, damaged, bruised or scarred.
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Now clean the skin with the alcohol wipe.
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Do not touch the injection site again or blow on it before the injection.
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Let your skin dry before injection.
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Pick up the pen by holding the middle of the pen body, with the needle pointing away from you.
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With the other hand, pull the cap straight off.
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Once you’ve removed the cap, do not put it back on.
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Do not twist the cap off.
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Do not remove the cap until you are ready to inject.
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Do not press or touch the needle cover with your fingers. The needle is inside.
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Do not try to put the cap back on once you’ve removed it.
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Inject the medicine right away after removing the cap.
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Place the yellow needle cover on the skin at approximately a 90-degree angle.
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Make sure you can see the injector window.
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Press down and hold the pen firmly against the skin until you can no longer see the Needle Cover.
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There may be a “click” when the injection starts.
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As you hold the pen firmly against the skin, the injector window will start to turn yellow.
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The injection can take up to 20 seconds.
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You may hear a second click.
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Check that the entire Window has turned to yellow before removing the pen.
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Slowly count to 5, and then lift the pen up straight off the skin.
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That’s it! You’re done.
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If the Window does not turn fully Yellow,
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remove the pen and call your healthcare provider or Freedom support program nurse.
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Do not give a second dose without speaking to your healthcare provider.
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Lightly press a cotton ball or gauze on the injection site if you see any blood.
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You can also cover the site with a bandage.
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Your child should not rub their skin after the injection.
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Be sure to put the used pen and its cap into a puncture-resistant disposal container
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right away after use.
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Do not re-use the pre-filled pen.
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Do not dispose of pre-filled pens in your household trash.
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Do not recycle your used puncture resistant container.
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Follow your local guidelines and ask your pharmacy or healthcare provider for the appropriate way to dispose of your used pen.
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Be sure to keep track of the injection date and site.
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Thank you for joining us today.
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Remember you can rewatch this video as often as you like to refresh your memory.
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Contact your healthcare provider or the Freedom support program with any questions or concerns.
DUPIXENT® is not a steroid treatment or an immunosuppressant. DUPIXENT® is an immunomodulator.1
